› 4lsc

X-ray diffraction
1.53Å resolution

Isolated SERK1 co-receptor ectodomain at high resolution

Released:
DOI: 10.2210/pdb4lsc/pdb
PDB entry 4lsc coloured by chain, front view.
PDB entry 4lsc coloured by chain, side view.
PDB entry 4lsc coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Molecular mechanism for plant steroid receptor activation by somatic embryogenesis co-receptor kinases.
Santiago J, Henzler C, Hothorn M
Science 341 889-92 (2013)
PMID: 23929946

Function and Biology Details

Reactions catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188210 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Somatic embryogenesis receptor kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 24.38 KDa
Source organism: Arabidopsis thaliana
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q94AG2 (Residues: 24-213; Coverage: 31%)
Gene names: At1g71830, F14O23.21, F14O23_24, SERK1
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer
1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P61
Unit cell:
a: 72.63Å b: 72.63Å c: 80.97Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.177
Expression system: Trichoplusia ni

Quick links

Citations

60 review citations

Plant PRRs and the activation of innate immune signaling.
Macho et al. (2014)
59 more

5 mentions without citation

Plant Leucine-Rich Repeat Receptor Kinase (LRR-RK): Structure, Ligand Perception, and Activation Mechanism.
Chakraborty et al. (2019)
4 more