› 4lui

X-ray diffraction
1.6Å resolution

Crystal structure of Orotidine 5'-monophosphate decarboxylase from methanocaldococcus jannaschii

Released:
DOI: 10.2210/pdb4lui/pdb
PDB entry 4lui coloured by chain, front view.
PDB entry 4lui coloured by chain, side view.
PDB entry 4lui coloured by chain, top view.
Source organism: Methanocaldococcus jannaschii DSM 2661
Entry authors: Fedorov AA, Fedorov EV, Desai B, Gerlt JA, Almo SC

Function and Biology Details

Reaction catalysed: 
Orotidine 5'-phosphate = UMP + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176459 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Orotidine 5'-phosphate decarboxylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 233 amino acids
Theoretical weight: 25.8 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli
UniProt:
  • Canonical: Q57700 (Residues: 1-213; Coverage: 100%)
Gene names: MJ0252, pyrF
Sequence domains: Orotidine 5'-phosphate decarboxylase / HUMPS family
Structure domains: Aldolase class I

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 47.88Å b: 49.783Å c: 168.604Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.175 0.2
Expression system: Escherichia coli

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