› 4o5h

X-ray diffraction
2Å resolution

X-ray crystal structure of a putative phenylacetaldehyde dehydrogenase from Burkholderia cenocepacia

Released:
DOI: 10.2210/pdb4o5h/pdb
PDB entry 4o5h coloured by chain, front view.
PDB entry 4o5h coloured by chain, side view.
PDB entry 4o5h coloured by chain, top view.
Source organism: Burkholderia cenocepacia J2315
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
Phenylacetaldehyde + NAD(+) + H(2)O = phenylacetate + NADH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-110042 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldehyde dehydrogenase domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 511 amino acids
Theoretical weight: 54.49 KDa
Source organism: Burkholderia cenocepacia J2315
Expression system: Escherichia coli
UniProt:
  • Canonical: B4EH14 (Residues: 2-503; Coverage: 100%)
Gene name: BCAM2298
Sequence domains: Aldehyde dehydrogenase family
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand GOL 6 x GOL
Ligand EDO 2 x EDO
Ligand NA 4 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: C2221
Unit cell:
a: 112.62Å b: 150.07Å c: 345.91Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.169 0.193
Expression system: Escherichia coli

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