› 4oqc

X-ray diffraction
1.3Å resolution

Urate OXIDASE CO-CRYSTALLIZED WITH AZIDE

Released:
DOI: 10.2210/pdb4oqc/pdb
PDB entry 4oqc coloured by chain, front view.
PDB entry 4oqc coloured by chain, side view.
PDB entry 4oqc coloured by chain, top view.
Source organism: Aspergillus flavus
Primary publication:
Azide inhibition of urate oxidase.
Gabison L, Colloc'h N, Prangé T
Acta Crystallogr F Struct Biol Commun 70 896-902 (2014)
PMID: 25005084

Function and Biology Details

Reaction catalysed: 
Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uricase Chain: A
Molecule details ›
Chain: A
Length: 302 amino acids
Theoretical weight: 34.18 KDa
Source organism: Aspergillus flavus
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q00511 (Residues: 2-302; Coverage: 100%)
Gene names: Uox, uaZ
Sequence domains: Uricase
Structure domains: Urate Oxidase;

Ligands and Environments

2 bound ligands:
Ligand AZI 2 x AZI
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: I222
Unit cell:
a: 78.77Å b: 94.85Å c: 104.34Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.188 not available
Expression system: Saccharomyces cerevisiae

Quick links

Citations

2 citation in other articles

Generation of Superoxide by OeRbohH, a NADPH Oxidase Activity During Olive (Olea europaea L.) Pollen Development and Germination.
Jimenez-Quesada et al. (2019)
1 more

3 mentions without citation

Import of proteins into peroxisomes: piggybacking to a new home away from home.
Thoms S. (2015)
2 more