› 4s30

X-ray diffraction
2Å resolution

ERK2 intrinsically active mutant (I84A)

Released:
DOI: 10.2210/pdb4s30/pdb
PDB entry 4s30 coloured by chain, front view.
PDB entry 4s30 coloured by chain, side view.
PDB entry 4s30 coloured by chain, top view.
Source organism: Rattus norvegicus
Entry authors: Livnah O, Karamansha Y

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158941 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 358 amino acids
Theoretical weight: 41.29 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P63086 (Residues: 1-358; Coverage: 100%)
Gene names: Erk2, Mapk, Mapk1, Prkm1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 49.017Å b: 69.542Å c: 59.798Å
α: 90° β: 109.06° γ: 90°
R-values:
R R work R free
0.197 0.194 0.249
Expression system: Escherichia coli

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