› 4wbc

X-ray diffraction
2.14Å resolution

2.13 A STRUCTURE OF A KUNITZ-TYPE WINGED BEAN CHYMOTRYPSIN INHIBITOR PROTEIN

Released:
DOI: 10.2210/pdb4wbc/pdb
PDB entry 4wbc coloured by chain, front view.
PDB entry 4wbc coloured by chain, side view.
PDB entry 4wbc coloured by chain, top view.
Source organism: Psophocarpus tetragonolobus
Primary publication:
Cryocrystallography of a Kunitz-type serine protease inhibitor: the 90 K structure of winged bean chymotrypsin inhibitor (WCI) at 2.13 A resolution.
Ravichandran S, Sen U, Chakrabarti C, Dattagupta JK
Acta Crystallogr D Biol Crystallogr 55 1814-21 (1999)
PMID: 10531477

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-145463 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chymotrypsin inhibitor 3 Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 20.27 KDa
Source organism: Psophocarpus tetragonolobus
UniProt:
  • Canonical: P10822 (Residues: 25-207; Coverage: 100%)
Sequence domains: Trypsin and protease inhibitor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

1 bound ligand:
Ligand SO4 5 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P6122
Unit cell:
a: 60.84Å b: 60.84Å c: 207.91Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.199 0.257

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Citations

1 review citation

A novel subclassification for Kunitz proteinase inhibitors from leguminous seeds.
Oliva et al. (2010)
11 other articles

2 mentions without citation

The Sequence and Three-Dimensional Structure Characterization of Snake Venom Phospholipases B.
Ullah et al. (2020)
1 more