› 4yvd

X-ray diffraction
1.7Å resolution

Crytsal structure of human Pleiotropic Regulator 1 (PRL1)

Released:
DOI: 10.2210/pdb4yvd/pdb
PDB entry 4yvd coloured by chain, front view.
PDB entry 4yvd coloured by chain, side view.
PDB entry 4yvd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dong A, Zeng H, Xu C, Tempel W, Li Y, He H, Bountra C, Arrowsmith CH, Edwards AM, Brown PJ, Min J, Wu H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129054 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pleiotropic regulator 1 Chain: A
Molecule details ›
Chain: A
Length: 374 amino acids
Theoretical weight: 41.67 KDa
Source organism: Homo sapiens
Expression system: Insect cell expression vector pTIE1
UniProt:
  • Canonical: O43660 (Residues: 141-514; Coverage: 73%)
Gene name: PLRG1
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

3 bound ligands:
Ligand NA 1 x NA
Ligand CL 5 x CL
Ligand UNX 12 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21212
Unit cell:
a: 158.33Å b: 34.185Å c: 48.818Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.187 0.22
Expression system: Insect cell expression vector pTIE1

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