Function and Biology Details
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152414 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Pre-mRNA-splicing helicase BRR2
Molecule details ›
Chain: A
Length: 1948 amino acids
Theoretical weight: 222.15 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 1948 amino acids
Theoretical weight: 222.15 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P32639 (Residues: 113-2163; Coverage: 90%)
Sequence domains:
- Pre-mRNA-splicing helicase BRR2 plug domain
- N-terminal helicase PWI domain
- DEAD/DEAH box helicase
- Helicase conserved C-terminal domain
- Sec63 Brl domain
Pre-mRNA-splicing factor 8
Molecule details ›
Chain: J
Length: 251 amino acids
Theoretical weight: 28.51 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: PROCT (NUC072) domain
Structure domains: Cytidine Deaminase, domain 2
Length: 251 amino acids
Theoretical weight: 28.51 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: P33334 (Residues: 2148-2398; Coverage: 10%)
Sequence domains: PROCT (NUC072) domain
Structure domains: Cytidine Deaminase, domain 2
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup:
P212121
Expression systems:
- Trichoplusia ni
- Escherichia coli
