› 5f4o

X-ray diffraction
1.59Å resolution

Protruding domain of GII.17 norovirus Kawasaki308

Released:
DOI: 10.2210/pdb5f4o/pdb
PDB entry 5f4o coloured by chain, front view.
PDB entry 5f4o coloured by chain, side view.
PDB entry 5f4o coloured by chain, top view.
Source organism: Norovirus Hu/GII/JP/2015/GII.P17_GII.17/Kawasaki308
Primary publication:
Structural Evolution of the Emerging 2014-2015 GII.17 Noroviruses.
Singh BK, Koromyslova A, Hefele L, Gürth C, Hansman GS
J Virol 90 2710-5 (2015)
PMID: 26699640

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101223 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 307 amino acids
Theoretical weight: 34.26 KDa
Source organism: Norovirus Hu/GII/JP/2015/GII.P17_GII.17/Kawasaki308
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0E4B1P1 (Residues: 225-530; Coverage: 57%)
Gene name: VP1
Sequence domains: Calicivirus coat protein C-terminal
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand EDO 9 x EDO
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P212121
Unit cell:
a: 75.72Å b: 86.97Å c: 97.35Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.153 0.151 0.174
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Burden of acute gastroenteritis caused by norovirus in China: A systematic review.
Zhou et al. (2017)
3 more

6 mentions without citation

Structural Evolution of the Emerging 2014-2015 GII.17 Noroviruses.
Singh et al. (2015)
5 more