› 5frr

X-ray diffraction
5.8Å resolution

Structure of the Pds5-Scc1 complex and implications for cohesin function

Released:
DOI: 10.2210/pdb5frr/pdb
PDB entry 5frr coloured by chain, front view.
PDB entry 5frr coloured by chain, side view.
PDB entry 5frr coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function.
Muir KW, Kschonsak M, Li Y, Metz J, Haering CH, Panne D
Cell Rep 14 2116-2126 (2016)
PMID: 26923589

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-215222 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sister chromatid cohesion protein PDS5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 703 amino acids
Theoretical weight: 80.74 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q04264 (Residues: 1-701; Coverage: 55%)
Gene names: PDS5, YM9582.01C, YM9916.15C, YMR076C
Sequence domains: Sister chromatid cohesion protein PDS5 protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: I422
Unit cell:
a: 283.69Å b: 283.69Å c: 172.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.249 0.311
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Structural Insights into Ring Formation of Cohesin and Related Smc Complexes.
Gligoris et al. (2016)
8 more