› 5h3s

X-ray diffraction
3Å resolution

apo form of GEMIN5-WD

Released:
DOI: 10.2210/pdb5h3s/pdb
PDB entry 5h3s coloured by chain, front view.
PDB entry 5h3s coloured by chain, side view.
PDB entry 5h3s coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for specific recognition of pre-snRNA by Gemin5.
Tang X, Bharath SR, Piao S, Tan VQ, Bowler MW, Song H
OpenAccess logo Cell Res 26 1353-1356 (2016)
PMID: 27834343

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gem-associated protein 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 740 amino acids
Theoretical weight: 82.3 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8TEQ6 (Residues: 1-740; Coverage: 49%)
Gene name: GEMIN5
Sequence domains:
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 76.503Å b: 91.373Å c: 112.571Å
α: 90° β: 100.55° γ: 90°
R-values:
R R work R free
0.204 0.201 0.261
Expression system: Spodoptera frugiperda

Quick links

Citations

4 review citations

Deciphering the mRNP Code: RNA-Bound Determinants of Post-Transcriptional Gene Regulation.
Gehring et al. (2017)
3 more

2 mentions without citation

Control of the eIF4E activity: structural insights and pharmacological implications.
Romagnoli et al. (2021)
1 more