› 5haz

X-ray diffraction
2.1Å resolution

Structure of Chaetomium thermophilum Nup170 CTD

Released:
DOI: 10.2210/pdb5haz/pdb
PDB entry 5haz coloured by chain, front view.
PDB entry 5haz coloured by chain, side view.
PDB entry 5haz coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Architecture of the symmetric core of the nuclear pore.
Lin DH, Stuwe T, Schilbach S, Rundlet EJ, Perriches T, Mobbs G, Fan Y, Thierbach K, Huber FM, Collins LN, Davenport AM, Jeon YE, Hoelz A
Science 352 aaf1015 (2016)
PMID: 27081075

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-515012 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin NUP170 Chain: A
Molecule details ›
Chain: A
Length: 567 amino acids
Theoretical weight: 63.48 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli
UniProt:
  • Canonical: G0S7B6 (Residues: 851-1416; Coverage: 40%)
Gene names: CTHT_0036270, NUP170
Sequence domains: Non-repetitive/WGA-negative nucleoporin C-terminal

Ligands and Environments

3 bound ligands:
Ligand EDO 2 x EDO
Ligand EPE 1 x EPE
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: C2
Unit cell:
a: 141.26Å b: 54.77Å c: 108.2Å
α: 90° β: 91.05° γ: 90°
R-values:
R R work R free
0.207 0.206 0.231
Expression system: Escherichia coli

Quick links

Citations

41 review citations

The nuclear pore complex: understanding its function through structural insight.
Beck et al. (2017)
40 more

3 mentions without citation

Architecture of the symmetric core of the nuclear pore.
Lin et al. (2016)
2 more