› 5hb4

X-ray diffraction
3.2Å resolution

Crystal structure of Chaetomium thermophilum Nup192

Released:
DOI: 10.2210/pdb5hb4/pdb
PDB entry 5hb4 coloured by chain, front view.
PDB entry 5hb4 coloured by chain, side view.
PDB entry 5hb4 coloured by chain, top view.
Source organism: Thermochaetoides thermophila
Primary publication:
Architecture of the symmetric core of the nuclear pore.
Lin DH, Stuwe T, Schilbach S, Rundlet EJ, Perriches T, Mobbs G, Fan Y, Thierbach K, Huber FM, Collins LN, Davenport AM, Jeon YE, Hoelz A
Science 352 aaf1015 (2016)
PMID: 27081075

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-514969 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin NUP192 Chain: B
Molecule details ›
Chain: B
Length: 1596 amino acids
Theoretical weight: 178.43 KDa
Source organism: Thermochaetoides thermophila
Expression system: Escherichia coli
UniProt:
  • Canonical: G0S4T0 (Residues: 151-166, 185-1756; Coverage: 90%)
Gene names: CTHT_0023410, NUP192
Sequence domains: Nuclear pore complex scaffold, nucleoporins 186/192/205

Ligands and Environments

1 bound ligand:
Ligand OS 5 x OS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: C2
Unit cell:
a: 190.74Å b: 53.5Å c: 171.79Å
α: 90° β: 108.33° γ: 90°
R-values:
R R work R free
0.234 0.233 0.265
Expression system: Escherichia coli

Quick links

Citations

40 review citations

The nuclear pore complex: understanding its function through structural insight.
Beck et al. (2017)
39 more

5 mentions without citation

The Structure of the Nuclear Pore Complex (An Update).
Lin et al. (2019)
4 more