› 5hdg

X-ray diffraction
1.7Å resolution

crystal structure of heat shock factor 1-DBD

Released:
DOI: 10.2210/pdb5hdg/pdb
PDB entry 5hdg coloured by chain, front view.
PDB entry 5hdg coloured by chain, side view.
PDB entry 5hdg coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Feng H, Liu W, Wang DC

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-169459 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock factor protein 1 Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 13.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00613 (Residues: 15-120; Coverage: 20%)
Gene names: HSF1, HSTF1
Sequence domains: HSF-type DNA-binding
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: I222
Unit cell:
a: 48.61Å b: 64.42Å c: 68.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.191 0.218
Expression system: Escherichia coli

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