› 5hr1

X-ray diffraction
2.14Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141959 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin 1 Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 109 amino acids
Theoretical weight: 11.78 KDa
Source organism: Escherichia coli O157:H7
Expression system: Escherichia coli
UniProt:
  • Canonical: P0AA25 (Residues: 1-109; Coverage: 100%)
Gene names: JW5856, b3781, fipA, trxA, tsnC
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand CU 2 x CU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 85.412Å b: 88.693Å c: 115.459Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.235
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The Thioredoxin System of Mammalian Cells and Its Modulators.
Hasan et al. (2022)
3 other articles

1 mention without citation

Structural variability of E. coli thioredoxin captured in the crystal structures of single-point mutants.
Noguera et al. (2017)