Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Macrolide export protein MacA, alpha-hairpin domain superfamily
- RND efflux pump, membrane fusion protein, barrel-sandwich domain
- RND efflux pump, membrane fusion protein
- Outer membrane efflux protein
- ABC transporter-like, ATP-binding domain
- P-loop containing nucleoside triphosphate hydrolase
- Type I secretion outer membrane protein, TolC
- ABC3 transporter permease protein domain
4 more domains
Structure analysis Details
Assembly composition:
hetero undecamer (preferred)
Assembly name:
MacAB-TolC ABC transporter complex (preferred)
PDBe Complex ID:
PDB-CPX-136396 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Outer membrane protein TolC
Molecule details ›
Chains: A, B, C
Length: 479 amino acids
Theoretical weight: 52.51 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: Outer membrane efflux protein
Structure domains: Outer membrane efflux proteins (OEP)
Length: 479 amino acids
Theoretical weight: 52.51 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical:
P02930 (Residues: 23-493; Coverage: 100%)
Sequence domains: Outer membrane efflux protein
Structure domains: Outer membrane efflux proteins (OEP)
Macrolide export protein MacA
Molecule details ›
Chains: D, E, F, G, H, I
Length: 371 amino acids
Theoretical weight: 40.72 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: Barrel-sandwich domain of CusB or HlyD membrane-fusion
Length: 371 amino acids
Theoretical weight: 40.72 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P75830 (Residues: 1-371; Coverage: 100%)
Sequence domains: Barrel-sandwich domain of CusB or HlyD membrane-fusion
Macrolide export ATP-binding/permease protein MacB
Molecule details ›
