› 7uxz

X-ray diffraction
1.73Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145015 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: AAA, BBB, CCC, DDD, EEE, FFF
Molecule details ›
Chains: AAA, BBB, CCC, DDD, EEE, FFF
Length: 114 amino acids
Theoretical weight: 12.81 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DTC9 (Residues: 251-364; Coverage: 27%)
Gene name: N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

5 bound ligands:
Ligand GKP 1 x GKP
Ligand PEG 2 x PEG
Ligand GOL 3 x GOL
Ligand NA 1 x NA
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS SIRUS BEAMLINE MANACA
Spacegroup: P212121
Unit cell:
a: 43.669Å b: 120.655Å c: 128.503Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.174 0.215
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 citation in other articles

Serodominant SARS-CoV-2 Nucleocapsid Peptides Map to Unstructured Protein Regions.
Vandervaart et al. (2023)
2 more

1 mention without citation

Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor.
Mercaldi et al. (2022)