7x6c

Electron Microscopy
3.15Å resolution

Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class1

Released:
Source organism: Homo sapiens
Primary publication:
Molecular architecture of the Gαi-bound TRPC5 ion channel.
OpenAccess logo Nat Commun 14 2550 (2023)
PMID: 37137991
Related structures: EMD-33021

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-193913 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Short transient receptor potential channel 5 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 773 amino acids
Theoretical weight: 89.95 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9UL62 (Residues: 1-765; Coverage: 79%)
Gene names: TRP5, TRPC5
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.15Å
Relevant EMDB volumes: EMD-33021
Expression system: Homo sapiens