› 1jnd

X-ray diffraction
1.3Å resolution

Crystal structure of imaginal disc growth factor-2

Released:
DOI: 10.2210/pdb1jnd/pdb
PDB entry 1jnd coloured by chain, front view.
PDB entry 1jnd coloured by chain, side view.
PDB entry 1jnd coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster.
Varela PF, Llera AS, Mariuzza RA, Tormo J
J Biol Chem 277 13229-36 (2002)
PMID: 11821393

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194189 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Chitinase-like protein Idgf2 Chain: A
Molecule details ›
Chain: A
Length: 420 amino acids
Theoretical weight: 46.95 KDa
Source organism: Drosophila melanogaster
UniProt:
  • Canonical: Q9V3D4 (Residues: 21-440; Coverage: 100%)
Gene names: CG4475, Idgf2
Sequence domains: Glycosyl hydrolases family 18
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: P3221
Unit cell:
a: 106.345Å b: 106.345Å c: 89.987Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.176 0.202

Quick links

Citations

4 review citations

Helminth parasites--masters of regulation.
Maizels et al. (2004)
3 more

3 mentions without citation

Crystallographic refinement of ligand complexes.
Kleywegt GJ. (2007)
2 more