› 1log

X-ray diffraction
2.1Å resolution

X-RAY STRUCTURE OF A (ALPHA-MAN(1-3)BETA-MAN(1-4)GLCNAC)-LECTIN COMPLEX AT 2.1 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1log/pdb
Model geometry
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PDB entry 1log coloured by chain, front view.
PDB entry 1log coloured by chain, side view.
PDB entry 1log coloured by chain, top view.
Source organism: Lathyrus ochrus
Primary publication:
X-ray structure of a (alpha-Man(1-3)beta-Man(1-4)GlcNAc)-lectin complex at 2.1-A resolution. The role of water in sugar-lectin interaction.
Bourne Y, Rougé P, Cambillau C
J Biol Chem 265 18161-5 (1990)
PMID: 2211692

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137409 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Lectin beta-1 and beta-2 chains Chains: A, C
Molecule details ›
Chains: A, C
Length: 181 amino acids
Theoretical weight: 19.85 KDa
Source organism: Lathyrus ochrus
UniProt:
  • Canonical: P04122 (Residues: 1-181; Coverage: 100%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls
Mannose/glucose-specific lectin alpha 1 chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 52 amino acids
Theoretical weight: 5.78 KDa
Source organism: Lathyrus ochrus
UniProt:
  • Canonical: P12306 (Residues: 1-52; Coverage: 98%)
Sequence domains: Legume lectin domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
2 bound ligands:
Ligand CA 2 x CA
Ligand MN 2 x MN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
Spacegroup: P21212
Unit cell:
a: 137.1Å b: 63.3Å c: 54.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.175 not available

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Citations

3 review citations

Protein glycosylation. Structural and functional aspects.
Lis et al. (1993)
2 more

8 mentions without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)
7 more

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