› 1qjq

X-ray diffraction
2.95Å resolution

FERRIC HYDROXAMATE RECEPTOR FROM ESCHERICHIA COLI (FHUA)

Released:
DOI: 10.2210/pdb1qjq/pdb
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Source organism: Escherichia coli K-12
Primary publication:
Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA.
Ferguson AD, Braun V, Fiedler HP, Coulton JW, Diederichs K, Welte W
Protein Sci 9 956-63 (2000)
PMID: 10850805

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139315 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Ferrichrome outer membrane transporter/phage receptor Chain: A
Molecule details ›
Chain: A
Length: 725 amino acids
Theoretical weight: 80.05 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P06971 (Residues: 34-438, 439-747; Coverage: 100%)
Gene names: JW0146, b0150, fhuA, tonA
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GCN, KDO, GMH, GLC, GLA
Carbohydrate polymer
5 bound ligands:
Ligand FTT 6 x FTT
Ligand DPO 2 x DPO
Ligand PO4 2 x PO4
Ligand NI 1 x NI
Ligand PFC 1 x PFC
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: MAX II BEAMLINE I711
Spacegroup: P61
Unit cell:
a: 172.1Å b: 172.1Å c: 87.65Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.225 0.225 0.278
Expression system: Escherichia coli K-12

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Citations

35 review citations

Bacterial iron homeostasis.
Andrews et al. (2003)
34 more

5 mentions without citation

TonB-dependent transporters: regulation, structure, and function.
Noinaj et al. (2010)
4 more

PDB-REDO

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