Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138110 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cellular tumor antigen p53
Molecule details ›
Chain: A
Length: 22 amino acids
Theoretical weight: 2.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Transactivation domain 2
Length: 22 amino acids
Theoretical weight: 2.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P04637 (Residues: 41-62; Coverage: 6%)
Sequence domains: Transactivation domain 2
General transcription factor IIH subunit 1
Molecule details ›
Chain: B
Length: 110 amino acids
Theoretical weight: 12.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: TFIIH p62 subunit, N-terminal domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Length: 110 amino acids
Theoretical weight: 12.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P32780 (Residues: 1-108; Coverage: 20%)
Sequence domains: TFIIH p62 subunit, N-terminal domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment:
85%
Refinement method:
DGSA-distance geometry simulated annealing
Expression system: Escherichia coli
