› 2alg

X-ray diffraction
2.3Å resolution

Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens

Released:
DOI: 10.2210/pdb2alg/pdb
PDB entry 2alg coloured by chain, front view.
PDB entry 2alg coloured by chain, side view.
PDB entry 2alg coloured by chain, top view.
Source organism: Prunus persica
Primary publication:
Crystal structure of peach Pru p 3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens.
Pasquato N, Berni R, Folli C, Folloni S, Cianci M, Pantano S, Helliwell JR, Zanotti G
J Mol Biol 356 684-94 (2006)
PMID: 16388823

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160516 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-specific lipid-transfer protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 92 amino acids
Theoretical weight: 9.28 KDa
Source organism: Prunus persica
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P81402 (Residues: 1-91; Coverage: 100%)
Sequence domains: Protease inhibitor/seed storage/LTP family
Structure domains: Plant lipid-transfer and hydrophobic proteins

Ligands and Environments

4 bound ligands:
Ligand DAO 2 x DAO
Ligand HP6 1 x HP6
Ligand SO4 1 x SO4
Ligand P6G 1 x P6G
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P6522
Unit cell:
a: 102.378Å b: 102.378Å c: 77.295Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.204 0.262
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

The biochemistry and biology of extracellular plant lipid-transfer proteins (LTPs).
Yeats et al. (2008)
12 more

23 mentions without citation

Lipid transfer proteins: classification, nomenclature, structure, and function.
Salminen et al. (2016)
22 more