› 2efb

X-ray diffraction
2.94Å resolution

Crystal structure of the complex of goat lactoperoxidase with phosphate at 2.94 A resolution

Released:
DOI: 10.2210/pdb2efb/pdb
PDB entry 2efb coloured by chain, front view.
PDB entry 2efb coloured by chain, side view.
PDB entry 2efb coloured by chain, top view.
Source organism: Capra hircus
Entry authors: Singh AK, Hariprasad G, Prem Kumar R, Singh N, Bhushan A, Sharma S, Kaur P, Singh TP

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105074 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Lactoperoxidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 595 amino acids
Theoretical weight: 67.53 KDa
Source organism: Capra hircus
UniProt:
  • Canonical: A0A452E9Y6 (Residues: 118-712; Coverage: 86%)
Gene name: LPO
Sequence domains: Animal haem peroxidase
Structure domains: Haem peroxidase domain superfamily, animal type

Ligands and Environments


Cofactor: Ligand HEM 2 x HEM
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
6 bound ligands:
Ligand PO4 5 x PO4
Ligand CO3 2 x CO3
Ligand CA 2 x CA
Ligand CYN 1 x CYN
Ligand SCN 1 x SCN
Ligand OSM 1 x OSM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P1
Unit cell:
a: 59.199Å b: 75.587Å c: 83.808Å
α: 79.93° β: 77.86° γ: 72.5°
R-values:
R R work R free
0.184 0.18 0.219

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