› 2eha

X-ray diffraction
3.3Å resolution

Crystal structure of goat lactoperoxidase complexed with formate anion at 3.3 A resolution

Released:
DOI: 10.2210/pdb2eha/pdb
PDB entry 2eha coloured by chain, front view.
PDB entry 2eha coloured by chain, side view.
PDB entry 2eha coloured by chain, top view.
Source organism: Capra hircus
Entry authors: Singh AK, Ethayathulla AS, Singh N, Sharma S, Kaur P, Singh TP

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105074 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Lactoperoxidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 595 amino acids
Theoretical weight: 67.53 KDa
Source organism: Capra hircus
UniProt:
  • Canonical: A0A452E9Y6 (Residues: 118-712; Coverage: 86%)
Gene name: LPO
Sequence domains: Animal haem peroxidase
Structure domains: Haem peroxidase domain superfamily, animal type

Ligands and Environments


Cofactor: Ligand HEM 2 x HEM
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
5 bound ligands:
Ligand CA 2 x CA
Ligand CO3 2 x CO3
Ligand SCN 1 x SCN
Ligand FMT 4 x FMT
Ligand OSM 1 x OSM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P1
Unit cell:
a: 57.991Å b: 72.272Å c: 83.652Å
α: 85.45° β: 84.04° γ: 75.89°
R-values:
R R work R free
0.197 0.196 0.237

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