› 2h4b

Solution NMR

cis-4-aminomethylphenylazobenzoic acid-avian pancreatic polypeptide

Released:
DOI: 10.2210/pdb2h4b/pdb
PDB entry 2h4b coloured by chain, ensemble of 20 models, front view.
PDB entry 2h4b coloured by chain, ensemble of 20 models, side view.
PDB entry 2h4b coloured by chain, ensemble of 20 models, top view.
Source organism: Meleagris gallopavo
Primary publication:
A photoswitchable miniprotein based on the sequence of avian pancreatic polypeptide.
Jurt S, Aemissegger A, Güntert P, Zerbe O, Hilvert D
Angew Chem Int Ed Engl 45 6297-300 (2006)
PMID: 16933352

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159362 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Pancreatic polypeptide Chains: A, B
Molecule details ›
Chains: A, B
Length: 9 amino acids
Theoretical weight: 903 Da
Source organism: Meleagris gallopavo
Expression system: Not provided
UniProt:
  • Canonical: P68249 (Residues: 1-9; Coverage: 25%)
Gene name: PPY
Pancreatic polypeptide Chains: C, D
Molecule details ›
Chains: C, D
Length: 25 amino acids
Theoretical weight: 3.05 KDa
Source organism: Meleagris gallopavo
Expression system: Not provided
UniProt:
  • Canonical: P68249 (Residues: 13-36; Coverage: 67%)
Gene name: PPY
Sequence domains: Pancreatic hormone peptide

Ligands and Environments

1 bound ligand:
Ligand ZAB 2 x ZAB
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

4 review citations

Light-controlled tools.
Brieke et al. (2012)
3 more

1 mention without citation

Mapping the Azolog Space Enables the Optical Control of New Biological Targets.
Morstein et al. (2019)