› 2i37

X-ray diffraction
4.15Å resolution

Crystal structure of a photoactivated rhodopsin

Released:
DOI: 10.2210/pdb2i37/pdb
PDB entry 2i37 coloured by chain, front view.
PDB entry 2i37 coloured by chain, side view.
PDB entry 2i37 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Salom D, Lodowski DT, Stenkamp RE, Le Trong I, Golczak M, Jastrzebska B, Harris T, Ballesteros JA, Palczewski K
Proc Natl Acad Sci U S A 103 16123-8 (2006)
PMID: 17060607

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (5 distinct):
Rhodopsin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 349 amino acids
Theoretical weight: 39.06 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02699 (Residues: 1-348; Coverage: 100%)
Gene name: RHO
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, MAN, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P3112
Unit cell:
a: 161.245Å b: 161.245Å c: 143.442Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.378 0.377 0.382

Quick links

Citations

73 review citations

The structure and function of G-protein-coupled receptors.
Rosenbaum et al. (2009)
72 more

48 mentions without citation

Structure-function of the G protein-coupled receptor superfamily.
Katritch et al. (2013)
47 more