› 2v4j

X-ray diffraction
2.1Å resolution

THE CRYSTAL STRUCTURE OF Desulfovibrio vulgaris DISSIMILATORY SULFITE REDUCTASE BOUND TO DsrC PROVIDES NOVEL INSIGHTS INTO THE MECHANISM OF SULFATE RESPIRATION

Released:
DOI: 10.2210/pdb2v4j/pdb
PDB entry 2v4j coloured by chain, front view.
PDB entry 2v4j coloured by chain, side view.
PDB entry 2v4j coloured by chain, top view.
Source organism: Nitratidesulfovibrio vulgaris str. Hildenborough
Primary publication:
The crystal structure of Desulfovibrio vulgaris dissimilatory sulfite reductase bound to DsrC provides novel insights into the mechanism of sulfate respiration.
Oliveira TF, Vonrhein C, Matias PM, Venceslau SS, Pereira IA, Archer M
J Biol Chem 283 34141-9 (2008)
PMID: 18829451

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155317 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Sulfite reductase, dissimilatory-type subunit alpha Chains: A, D
Molecule details ›
Chains: A, D
Length: 437 amino acids
Theoretical weight: 49.15 KDa
Source organism: Nitratidesulfovibrio vulgaris str. Hildenborough
UniProt:
  • Canonical: P45574 (Residues: 1-437; Coverage: 100%)
Gene names: DVU_0402, dsrA, dsvA
Sequence domains: Nitrite and sulphite reductase 4Fe-4S domain
Structure domains:
Sulfite reductase, dissimilatory-type subunit beta Chains: B, E
Molecule details ›
Chains: B, E
Length: 381 amino acids
Theoretical weight: 42.57 KDa
Source organism: Nitratidesulfovibrio vulgaris str. Hildenborough
UniProt:
  • Canonical: P45575 (Residues: 1-381; Coverage: 100%)
Gene names: DVU_0403, dsrB, dsvB
Sequence domains:
Structure domains:
Sulfite reductase, dissimilatory-type subunit gamma Chains: C, F
Molecule details ›
Chains: C, F
Length: 105 amino acids
Theoretical weight: 11.89 KDa
Source organism: Nitratidesulfovibrio vulgaris str. Hildenborough
UniProt:
  • Canonical: P45573 (Residues: 1-105; Coverage: 100%)
Gene names: DVU_2776, dsvC
Sequence domains: DsrC like protein
Structure domains:

Ligands and Environments


Cofactor: Ligand SH0 2 x SH0

Cofactor: Ligand SRM 2 x SRM
2 bound ligands:
Ligand SF4 8 x SF4
Ligand SO3 2 x SO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 65.41Å b: 118.9Å c: 132.24Å
α: 90° β: 104.13° γ: 90°
R-values:
R R work R free
0.192 0.19 0.219

Quick links

Citations

8 review citations

Metalloproteins containing cytochrome, iron-sulfur, or copper redox centers.
Liu et al. (2014)
7 more

11 mentions without citation

Metabolic functions of the human gut microbiota: the role of metalloenzymes.
Rajakovich et al. (2019)
10 more