› 3r4h

X-ray diffraction
2.7Å resolution

Crystal structure of the 4-helix coiled coil CC-Tet-phi22

Released:
DOI: 10.2210/pdb3r4h/pdb
PDB entry 3r4h coloured by chain, front view.
PDB entry 3r4h coloured by chain, side view.
PDB entry 3r4h coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
A de novo peptide hexamer with a mutable channel.
Zaccai NR, Chi B, Thomson AR, Boyle AL, Bartlett GJ, Bruning M, Linden N, Sessions RB, Booth PJ, Brady RL, Woolfson DN
OpenAccess logo Nat Chem Biol 7 935-41 (2011)
PMID: 22037471

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163968 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
coiled coil helix CC-Tet-phi22 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 34 amino acids
Theoretical weight: 3.45 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PHI 6 x PHI

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P43212
Unit cell:
a: 84.84Å b: 84.84Å c: 58.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.201 0.27
Expression system: Not provided

Quick links

Citations

22 review citations

The coming of age of de novo protein design.
Huang et al. (2016)
21 more

2 mentions without citation

Strategies to control the binding mode of de novo designed protein interactions.
Der et al. (2013)
1 more