› 3ub7

X-ray diffraction
1.4Å resolution

Periplasmic portion of the Helicobacter pylori chemoreceptor TlpB with acetamide bound

Released:
DOI: 10.2210/pdb3ub7/pdb
Model geometry
Fit model/data
PDB entry 3ub7 coloured by chain, front view.
PDB entry 3ub7 coloured by chain, side view.
PDB entry 3ub7 coloured by chain, top view.
Source organism: Helicobacter pylori SS1
Primary publication:
Structure and proposed mechanism for the pH-sensing Helicobacter pylori chemoreceptor TlpB.
Goers Sweeney E, Henderson JN, Goers J, Wreden C, Hicks KG, Foster JK, Parthasarathy R, Remington SJ, Guillemin K
Structure 20 1177-88 (2012)
PMID: 22705207

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-110346 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Methyl-accepting chemotaxis transmembrane sensory protein (MCP-like protein) Chains: A, B
Molecule details ›
Chains: A, B
Length: 181 amino acids
Theoretical weight: 20.69 KDa
Source organism: Helicobacter pylori SS1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B6JPK4 (Residues: 30-208; Coverage: 32%)
Gene names: HPP12_0105, tlpB
Sequence domains: Single Cache domain 2
Structure domains: PAS domain

Ligands and Environments

3 bound ligands:
Ligand ACM 2 x ACM
Ligand SO4 2 x SO4
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 79.587Å b: 81.986Å c: 94.137Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.139 0.138 0.162
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

14 review citations

The effect of bacterial chemotaxis on host infection and pathogenicity.
Matilla et al. (2018)
13 more

3 mentions without citation

Sensory Repertoire of Bacterial Chemoreceptors.
Ortega et al. (2017)
2 more