› 4o8q

X-ray diffraction
2.15Å resolution

Crystal structure of bovine MHD domain of the COPI delta subunit at 2.15 A resolution

Released:
DOI: 10.2210/pdb4o8q/pdb
PDB entry 4o8q coloured by chain, front view.
PDB entry 4o8q coloured by chain, side view.
PDB entry 4o8q coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structure of the bovine COPI δ subunit μ homology domain at 2.15 Å resolution.
Lahav A, Rozenberg H, Parnis A, Cassel D, Adir N
Acta Crystallogr D Biol Crystallogr 71 1328-34 (2015)
PMID: 26057672

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156837 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coatomer subunit delta Chains: A, B
Molecule details ›
Chains: A, B
Length: 245 amino acids
Theoretical weight: 27.58 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P53619 (Residues: 268-511; Coverage: 48%)
Gene names: ARCN1, COPD
Sequence domains: Adaptor complexes medium subunit family

Ligands and Environments

1 bound ligand:
Ligand FMT 1 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 42.092Å b: 110.333Å c: 145.794Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.229
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Formation of COPI-coated vesicles at a glance.
Arakel et al. (2018)
2 other articles

3 mentions without citation

9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Dodonova et al. (2017)
2 more