Function and Biology Details
Reaction catalysed:
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140787 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Poly [ADP-ribose] polymerase 1, processed C-terminus
Molecule details ›
Chains: A, C
Length: 359 amino acids
Theoretical weight: 40.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 359 amino acids
Theoretical weight: 40.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P09874 (Residues: 661-1014; Coverage: 35%)
Sequence domains:
Structure domains:
Protein timeless homolog
Molecule details ›
Chains: B, D
Length: 103 amino acids
Theoretical weight: 11.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Timeless PAB domain
Length: 103 amino acids
Theoretical weight: 11.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9UNS1 (Residues: 1000-1098; Coverage: 8%)
Sequence domains: Timeless PAB domain
