› 4gsb

X-ray diffraction
1.8Å resolution

Monoclinic crystal form of the apo-ERK2

Released:
DOI: 10.2210/pdb4gsb/pdb
PDB entry 4gsb coloured by chain, front view.
PDB entry 4gsb coloured by chain, side view.
PDB entry 4gsb coloured by chain, top view.
Source organism: Rattus norvegicus
Entry authors: Pozharski E, Zhang J, Shapiro P

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158941 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 364 amino acids
Theoretical weight: 42.25 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P63086 (Residues: 1-358; Coverage: 100%)
Gene names: Erk2, Mapk, Mapk1, Prkm1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand GOL 6 x GOL
Ligand SO4 1 x SO4
Ligand PGE 1 x PGE
2 modified residues:
Ligand CSO 1 x CSO
Ligand CME 1 x CME

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21
Unit cell:
a: 48.78Å b: 69.97Å c: 59.89Å
α: 90° β: 108.96° γ: 90°
R-values:
R R work R free
0.156 0.154 0.199
Expression system: Escherichia coli

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