4lzf

X-ray diffraction
1.72Å resolution

A novel domain in the microcephaly protein CPAP suggests a role in centriole architecture

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-123080 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Centromere protein J C-terminal domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 20.86 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: E7FCY1 (Residues: 942-1121; Coverage: 16%)
Gene name: cenpj
Sequence domains: T-complex protein 10 C-terminus
Structure domains: lipopolysaccharide transport protein A fold
SCL-interrupting locus protein homolog Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.63 KDa
Source organism: Danio rerio
Expression system: Not provided
UniProt:
  • Canonical: Q8JGS1 (Residues: 414-428; Coverage: 1%)
Gene names: sill, stil, zgc:110502

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: C2
Unit cell:
a: 97.58Å b: 38.39Å c: 70.05Å
α: 90° β: 126.68° γ: 90°
R-values:
R R work R free
0.192 0.19 0.231
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided