› 4muu

X-ray diffraction
2.1Å resolution

Structure of ThiT with pyrithiamine bound

Released:
DOI: 10.2210/pdb4muu/pdb
PDB entry 4muu coloured by chain, front view.
PDB entry 4muu coloured by chain, side view.
PDB entry 4muu coloured by chain, top view.
Source organism: Lactococcus lactis subsp. cremoris NZ9000
Entry authors: Swier LJYM, Guskov A, Slotboom DJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164840 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thiamine transporter ThiT Chains: A, B
Molecule details ›
Chains: A, B
Length: 192 amino acids
Theoretical weight: 21.23 KDa
Source organism: Lactococcus lactis subsp. cremoris NZ9000
Expression system: Lactococcus lactis subsp. cremoris NZ9000
Structure domains: Arp2/3 complex 21 kDa subunit ARPC3

Ligands and Environments

9 bound ligands:
Ligand 218 2 x 218
Ligand BNG 3 x BNG
Ligand PEG 10 x PEG
Ligand PG0 8 x PG0
Ligand PG4 9 x PG4
Ligand 1PE 1 x 1PE
Ligand PGE 3 x PGE
Ligand P6G 4 x P6G
Ligand PE5 1 x PE5
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2
Unit cell:
a: 61.56Å b: 84.59Å c: 127.26Å
α: 90° β: 95.61° γ: 90°
R-values:
R R work R free
0.196 0.194 0.236
Expression system: Lactococcus lactis subsp. cremoris NZ9000

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