Function and Biology Details
Reaction catalysed:
NADPH + NAD(+) + H(+)(Side 1) = NADP(+) + H(+)(Side 2) + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain
- Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal
- Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2
- NAD(P)-binding domain superfamily
- DHS-like NAD/FAD-binding domain superfamily
- NADP transhydrogenase beta-like domain
- NADP transhydrogenase, beta subunit
- NAD(P) transhydrogenase, alpha subunit, C-terminal
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180813 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
proton-translocating NAD(P)(+) transhydrogenase
Molecule details ›
Chains: A, C
Length: 100 amino acids
Theoretical weight: 10.65 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
Sequence domains: 4TM region of pyridine nucleotide transhydrogenase, mitoch
Length: 100 amino acids
Theoretical weight: 10.65 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
- Canonical:
Q72GR9 (Residues: 1-100; Coverage: 100%)
Sequence domains: 4TM region of pyridine nucleotide transhydrogenase, mitoch
NAD(P) transhydrogenase subunit beta
Molecule details ›
Chains: B, D
Length: 450 amino acids
Theoretical weight: 47.37 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
Sequence domains: NAD(P) transhydrogenase beta subunit
Length: 450 amino acids
Theoretical weight: 47.37 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
- Canonical: Q72GS0 (Residues: 1-450; Coverage: 100%)
Sequence domains: NAD(P) transhydrogenase beta subunit
proton-translocating NAD(P)(+) transhydrogenase
Molecule details ›
Chains: E, F
Length: 384 amino acids
Theoretical weight: 41.26 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 384 amino acids
Theoretical weight: 41.26 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
- Canonical: Q72GR8 (Residues: 1-375; Coverage: 100%)
Sequence domains:
