› 4ra1

X-ray diffraction
1.75Å resolution

PBP AccA from A. tumefaciens C58 in complex with D-Glucose-2-phosphate

Released:
DOI: 10.2210/pdb4ra1/pdb
PDB entry 4ra1 coloured by chain, front view.
PDB entry 4ra1 coloured by chain, side view.
PDB entry 4ra1 coloured by chain, top view.
Source organism: Agrobacterium tumefaciens
Primary publication:
A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens.
El Sahili A, Li SZ, Lang J, Virus C, Planamente S, Ahmar M, Guimaraes BG, Aumont-Nicaise M, Vigouroux A, Soulère L, Reader J, Queneau Y, Faure D, Moréra S
OpenAccess logo PLoS Pathog 11 e1005071 (2015)
PMID: 26244338

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-175996 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute-binding protein family 5 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 499 amino acids
Theoretical weight: 57.18 KDa
Source organism: Agrobacterium tumefaciens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q52012 (Residues: 30-521; Coverage: 99%)
Gene names: Atu6139, accA
Sequence domains: Bacterial extracellular solute-binding proteins, family 5 Middle
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand ALX 1 x ALX
Ligand BNX 1 x BNX
Ligand PEG 2 x PEG
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: C2221
Unit cell:
a: 77.21Å b: 113.87Å c: 113.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.172 0.202
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Quorum Sensing and Quorum Quenching in Agrobacterium: A "Go/No Go System"?
Dessaux et al. (2018)
4 more

1 mention without citation

A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens.
El Sahili et al. (2015)