› 4za6

X-ray diffraction
1.97Å resolution

Structure of the R. erythropolis transcriptional repressor QsdR from TetR family

Released:
DOI: 10.2210/pdb4za6/pdb
PDB entry 4za6 coloured by chain, front view.
PDB entry 4za6 coloured by chain, side view.
PDB entry 4za6 coloured by chain, top view.
Source organism: Rhodococcus erythropolis
Primary publication:
Natural Guided Genome Engineering Reveals Transcriptional Regulators Controlling Quorum-Sensing Signal Degradation.
El Sahili A, Kwasiborski A, Mothe N, Velours C, Legrand P, Moréra S, Faure D
OpenAccess logo PLoS One 10 e0141718 (2015)
PMID: 26554837

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101050 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
QsdR TetR regulatory C-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 192 amino acids
Theoretical weight: 21.3 KDa
Source organism: Rhodococcus erythropolis
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0C2W9F0 (Residues: 1-186; Coverage: 100%)
Gene names: I3517_23075, QIE55_27000
Sequence domains: Tetracyclin repressor-like, C-terminal domain

Ligands and Environments

3 bound ligands:
Ligand MPD 6 x MPD
Ligand ACT 2 x ACT
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: I41
Unit cell:
a: 91.63Å b: 91.63Å c: 145.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.206 0.228
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Biosensors Used for Epifluorescence and Confocal Laser Scanning Microscopies to Study Dickeya and Pectobacterium Virulence and Biocontrol.
Bourigault et al. (2021)

3 mentions without citation

A Rhodococcal Transcriptional Regulatory Mechanism Detects the Common Lactone Ring of AHL Quorum-Sensing Signals and Triggers the Quorum-Quenching Response.
Barbey et al. (2018)
2 more