5j5t

X-ray diffraction
2.85Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-184872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase kinase kinase kinase 3 Chain: A
Molecule details ›
Chain: A
Length: 370 amino acids
Theoretical weight: 42.23 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: Q8IVH8 (Residues: 13-380; Coverage: 41%)
Gene names: MAP4K3, RAB8IPL1
Sequence domains: Protein kinase domain
Structure domains: Transferase(Phosphotransferase) domain 1

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: C2
Unit cell:
a: 92.703Å b: 63.324Å c: 64.916Å
α: 90° β: 116.04° γ: 90°
R-values:
R R work R free
0.177 0.175 0.206
Expression system: unidentified baculovirus