› 5mzr

X-ray diffraction
2.65Å resolution

X-ray structure of the H235Q mutant of GLIC in complex with propofol

Released:
DOI: 10.2210/pdb5mzr/pdb
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PDB entry 5mzr coloured by chain, front view.
PDB entry 5mzr coloured by chain, side view.
PDB entry 5mzr coloured by chain, top view.
Source organism: Gloeobacter violaceus PCC 7421
Entry authors: Fourati Z, Delarue M

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proton-gated ion channel Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 327 amino acids
Theoretical weight: 37.41 KDa
Source organism: Gloeobacter violaceus PCC 7421
Expression system: Gloeobacter violaceus PCC 7421
UniProt:
  • Canonical: Q7NDN8 (Residues: 43-359; Coverage: 100%)
Gene names: glr4197, glvI
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains:

Ligands and Environments

6 bound ligands:
Ligand PLC 15 x PLC
Ligand CL 7 x CL
Ligand NA 6 x NA
Ligand ACT 10 x ACT
Ligand LMT 6 x LMT
Ligand PFL 4 x PFL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 182.842Å b: 132.989Å c: 161.162Å
α: 90° β: 102.83° γ: 90°
R-values:
R R work R free
0.192 0.191 0.21
Expression system: Gloeobacter violaceus PCC 7421

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