› 5odm

Solution NMR

NtiPr polyamide in complex with 5'CGATGTACTACG3

Released:
DOI: 10.2210/pdb5odm/pdb
PDB entry 5odm coloured by chain, ensemble of 10 models, front view.
PDB entry 5odm coloured by chain, ensemble of 10 models, side view.
PDB entry 5odm coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of DNA duplex distortion induced by thiazole-containing hairpin polyamides.
Padroni G, Parkinson JA, Fox KR, Burley GA
Nucleic Acids Res 46 42-53 (2018)
PMID: 29194552

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-119095 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*AP*TP*GP*TP*AP*CP*AP*TP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.58 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

5 bound ligands:
Ligand 9U2 1 x 9U2
Ligand PYB 6 x PYB
Ligand ABU 1 x ABU
Ligand IMT 1 x IMT
Ligand 9T8 1 x 9T8
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 58%
Refinement method: matrix relaxation
Expression system: Not provided

Quick links

Citations

1 review citation

Molecules targeting the androgen receptor (AR) signaling axis beyond the AR-Ligand binding domain.
Elshan et al. (2019)
2 other articles

3 mentions without citation

A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding.
Satange et al. (2018)
2 more