› 5oml

X-ray diffraction
1.5Å resolution

Crystal structure of Trypanosoma Brucei PEX14 N-terminal domain in complex with small molecules to investigate the water envelope

Released:
DOI: 10.2210/pdb5oml/pdb
PDB entry 5oml coloured by chain, front view.
PDB entry 5oml coloured by chain, side view.
PDB entry 5oml coloured by chain, top view.
Source organism: Trypanosoma brucei brucei
Entry authors: Ratkova EL, Dawidowski M, Napolitano V, Dubin G, Fino R, Popowicz G, Sattler M, Tetko IV

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184760 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisomal membrane protein PEX14 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 67 amino acids
Theoretical weight: 7.75 KDa
Source organism: Trypanosoma brucei brucei
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IEW2 (Residues: 20-84; Coverage: 18%)
Gene name: PEX14
Sequence domains: Pex14 N-terminal domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

3 bound ligands:
Ligand 9YB 4 x 9YB
Ligand SO4 5 x SO4
Ligand BME 4 x BME
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, DESY BEAMLINE P11
Spacegroup: P21
Unit cell:
a: 35.863Å b: 116.368Å c: 38.962Å
α: 90° β: 101.46° γ: 90°
R-values:
R R work R free
0.178 0.176 0.202
Expression system: Escherichia coli

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