› 5qtf

X-ray diffraction
1.78Å resolution

T. brucei FPPS in complex with CID 144539

Released:
DOI: 10.2210/pdb5qtf/pdb
PDB entry 5qtf coloured by chain, front view.
PDB entry 5qtf coloured by chain, side view.
PDB entry 5qtf coloured by chain, top view.
Source organism: Trypanosoma brucei
Entry authors: Muenzker L, Petrick JK, Schleberger C, Cornaciu I, Marquez JA, Jahnke W

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183122 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl pyrophosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 369 amino acids
Theoretical weight: 42.17 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q86C09 (Residues: 1-367; Coverage: 100%)
Sequence domains: Polyprenyl synthetase

Ligands and Environments

4 bound ligands:
Ligand PK7 1 x PK7
Ligand PO4 2 x PO4
Ligand NA 1 x NA
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P6122
Unit cell:
a: 60.623Å b: 60.623Å c: 341.323Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.252 0.25 0.293
Expression system: Escherichia coli BL21(DE3)

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