Function and Biology Details
Reaction catalysed:
Succinate + a quinone = fumarate + a quinol
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Fumarate reductase, subunit D
- Fumarate reductase, subunit C
- Fumarate reductase/succinate dehydrogenase, transmembrane subunit
- 4Fe-4S ferredoxin-type, iron-sulphur binding domain
- 2Fe-2S ferredoxin-type iron-sulfur binding domain
- Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily
- FAD/NAD(P)-binding domain superfamily
- 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
13 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Plasma membrane fumarate reductase complex (preferred)
PDBe Complex ID:
PDB-CPX-132435 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Fumarate reductase flavoprotein subunit
Molecule details ›
Chains: A, E
Length: 585 amino acids
Theoretical weight: 64.34 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 585 amino acids
Theoretical weight: 64.34 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical:
P00363 (Residues: 1-585; Coverage: 97%)
Sequence domains:
Fumarate reductase iron-sulfur subunit
Molecule details ›
Chains: B, F
Length: 243 amino acids
Theoretical weight: 27.02 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 243 amino acids
Theoretical weight: 27.02 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P0AC47 (Residues: 2-244; Coverage: 100%)
Sequence domains:
Fumarate reductase subunit C
Molecule details ›
Chains: C, G
Length: 130 amino acids
Theoretical weight: 14.9 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: Fumarate reductase subunit C
Length: 130 amino acids
Theoretical weight: 14.9 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P0A8Q0 (Residues: 2-131; Coverage: 99%)
Sequence domains: Fumarate reductase subunit C
Fumarate reductase subunit D
Molecule details ›
Chains: D, H
Length: 119 amino acids
Theoretical weight: 13.12 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: Fumarate reductase subunit D
Length: 119 amino acids
Theoretical weight: 13.12 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P0A8Q3 (Residues: 1-119; Coverage: 100%)
Sequence domains: Fumarate reductase subunit D
