› 5z4w

X-ray diffraction
1.79Å resolution

Crystal structure of signalling protein from buffalo (SPB-40) with an altered conformation of Trp78 at 1.79 A resolution

Released:
DOI: 10.2210/pdb5z4w/pdb
PDB entry 5z4w coloured by chain, front view.
PDB entry 5z4w coloured by chain, side view.
PDB entry 5z4w coloured by chain, top view.
Source organism: Bubalus bubalis
Primary publication:
A glycoprotein from mammary gland secreted during involution promotes apoptosis: Structural and biological studies.
Chaudhary A, Kumar V, Singh PK, Sharma P, Bairagya HR, Kaur P, Sharma S, Chauhan SS, Singh TP
Arch Biochem Biophys 644 72-80 (2018)
PMID: 29524427

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182210 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chitinase-3-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 361 amino acids
Theoretical weight: 40.71 KDa
Source organism: Bubalus bubalis
UniProt:
  • Canonical: Q7YS85 (Residues: 22-383; Coverage: 100%)
Gene names: CHI3L1, MGP-40
Sequence domains: Glycosyl hydrolases family 18

Ligands and Environments

3 bound ligands:
Ligand NAG 1 x NAG
Ligand MPD 1 x MPD
Ligand EOH 1 x EOH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P212121
Unit cell:
a: 61.068Å b: 66.735Å c: 106.072Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.152 0.15 0.186

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