6mrc

Electron Microscopy
3.08Å resolution

ADP-bound human mitochondrial Hsp60-Hsp10 football complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 28-mer (preferred)
PDBe Complex ID:
PDB-CPX-145457 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
60 kDa heat shock protein, mitochondrial Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Length: 528 amino acids
Theoretical weight: 56.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10809 (Residues: 27-552; Coverage: 92%)
Gene names: HSP60, HSPD1
Sequence domains: TCP-1/cpn60 chaperonin family
10 kDa heat shock protein, mitochondrial Chains: 1, 2, O, P, Q, R, S, T, U, V, W, X, Y, Z
Molecule details ›
Chains: 1, 2, O, P, Q, R, S, T, U, V, W, X, Y, Z
Length: 100 amino acids
Theoretical weight: 10.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61604 (Residues: 3-102; Coverage: 98%)
Gene name: HSPE1
Sequence domains: Chaperonin 10 Kd subunit

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.08Å
Relevant EMDB volumes: EMD-9195
Expression system: Escherichia coli