Function and Biology Details
Reaction catalysed:
(R)-mevalonate + CoA + 2 NAD(+) = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Hydroxymethylglutaryl-CoA reductase, class I/II
- Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site
- Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily
- Hydroxymethylglutaryl-CoA reductase, bacterial-type
- Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily
- Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
3-hydroxy-3-methylglutaryl coenzyme A reductase (preferred)
PDBe Complex ID:
PDB-CPX-108834 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):