› 6exs

X-ray diffraction
2.5Å resolution

Crystal structure of a POT family transporter in complex with thioalcohol conjugated peptide.

Released:
DOI: 10.2210/pdb6exs/pdb
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PDB entry 6exs coloured by chain, front view.
PDB entry 6exs coloured by chain, side view.
PDB entry 6exs coloured by chain, top view.
Source organism: Staphylococcus hominis
Primary publication:
Structural basis of malodour precursor transport in the human axilla.
Minhas GS, Bawdon D, Herman R, Rudden M, Stone AP, James AG, Thomas GH, Newstead S
OpenAccess logo Elife 7 (2018)
PMID: 29966586

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166686 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide ABC transporter permease Chain: A
Molecule details ›
Chain: A
Length: 487 amino acids
Theoretical weight: 53.82 KDa
Source organism: Staphylococcus hominis
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

2 bound ligands:
Ligand OLC 13 x OLC
Ligand C3H 1 x C3H
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 60.04Å b: 55.576Å c: 100.866Å
α: 90° β: 104.75° γ: 90°
R-values:
R R work R free
0.212 0.211 0.235
Expression system: Escherichia coli BL21(DE3)

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Citations

4 review citations

Volatilomes of Bacterial Infections in Humans.
Elmassry et al. (2020)
3 more

8 mentions without citation

Recent advances in understanding prodrug transport through the SLC15 family of proton-coupled transporters.
Minhas et al. (2020)
7 more

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