› 6iz5

X-ray diffraction
3.7Å resolution

Crystal Structure Analysis of a Eukaryotic Membrane Protein

Released:
DOI: 10.2210/pdb6iz5/pdb
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PDB entry 6iz5 coloured by chain, front view.
PDB entry 6iz5 coloured by chain, side view.
PDB entry 6iz5 coloured by chain, top view.
Source organism: Xenopus laevis
Primary publication:
Structural basis for activity of TRIC counter-ion channels in calcium release.
Wang XH, Su M, Gao F, Xie W, Zeng Y, Li DL, Liu XL, Zhao H, Qin L, Li F, Liu Q, Clarke OB, Lam SM, Shui GH, Hendrickson WA, Chen YH
Proc Natl Acad Sci U S A 116 4238-4243 (2019)
PMID: 30770441

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179709 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trimeric intracellular cation channel type B-B Chain: A
Molecule details ›
Chain: A
Length: 314 amino acids
Theoretical weight: 35.46 KDa
Source organism: Xenopus laevis
Expression system: Schizosaccharomyces
UniProt:
  • Canonical: Q6GN30 (Residues: 1-284; Coverage: 100%)
Gene name: tmem38b-b
Sequence domains: TRIC channel

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: F432
Unit cell:
a: 250.009Å b: 250.009Å c: 250.009Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.312 0.311 0.327
Expression system: Schizosaccharomyces

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Citations

4 review citations

Collagen transport and related pathways in Osteogenesis Imperfecta.
Claeys et al. (2021)
3 more

1 mention without citation

Structural basis for activity of TRIC counter-ion channels in calcium release.
Wang et al. (2019)

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