› 6ku6

X-ray diffraction
2.01Å resolution

Function and Biology Details

Reaction catalysed: 
Succinate + NAD(+) = fumarate + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149225 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fumarate reductase 2 Chains: B, H
Molecule details ›
Chains: B, H
Length: 471 amino acids
Theoretical weight: 51.51 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P21375 (Residues: 32-501; Coverage: 94%)
Gene names: J1659, OSM1, YJR051W
Sequence domains: FAD binding domain

Ligands and Environments


Cofactor: Ligand FAD 2 x FAD
1 bound ligand:
Ligand SIN 2 x SIN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P21
Unit cell:
a: 51.924Å b: 109.924Å c: 77.142Å
α: 90° β: 98.52° γ: 90°
R-values:
R R work R free
0.201 0.2 0.25
Expression system: Escherichia coli

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